Biphasic Calcium Phosphate Ceramics for Bone Regeneration and Tissue Engineering Applications

Materials

Sonja Ellen Lobo¹ 

[1] Department of Morphology, Federal University of São Paulo, Rua Botucatu, 740, CEP 04023-900, São Paulo, SP, Brazil; E-Mail:

关键词: calcium phosphate ceramics;    bone reconstruction;    tissue engineering;    stem cell;   

DOI  :  10.3390/ma3020815

来源: mdpi

【 摘 要 】

Biphasic calcium phosphates (BCP) have been sought after as biomaterials for the reconstruction of bone defects in maxillofacial, dental and orthopaedic applications. They have demonstrated proven biocompatibility, osteoconductivity, safety and predictability in in vitro, in vivo and clinical models. More recently, in vitro and in vivo studies have shown that BCP can be osteoinductive. In the field of tissue engineering, they represent promising scaffolds capable of carrying and modulating the behavior of stem cells. This review article will highlight the latest advancements in the use of BCP and the characteristics that create a unique microenvironment that favors bone regeneration.

【 授权许可】

CC BY   
© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.