期刊论文详细信息
Molecules | |
Total Synthesis of Annonaceous Acetogenins Belonging to the Non-Adjacent Bis-THF and Non-Adjacent THF-THP Sub-Classes | |
Ian B. Spurr1  | |
[1] The School of Chemistry, The University of Southampton, Highfield, Southampton SO17 1BJ, UK | |
关键词: annonaceous acetogenins; non-adjacent bis-THF; tetrahydrofuran; tetrahydropyran; asymmetric synthesis; 1; 2-diols; epoxides; cytotoxic natural products; anti-tumour; | |
DOI : 10.3390/molecules15010460 | |
来源: mdpi | |
【 摘 要 】
The synthesis of the subgroups of acetogenins containing non-adjacent bis-THF and non-adjacent THF-THP core units is reviewed. Specifically, total syntheses of gigantecin, 4-deoxygigantecin, cis-sylvaticin, squamostatin-C, squamostatin-D, sylvaticin and mucocin are discussed.
【 授权许可】
CC BY
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
【 预 览 】
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