Self-Assembled Hydrogel Nanoparticles for Drug Delivery Applications

Materials

Catarina Gon๺lves¹  Paula Pereira¹ 

[1] IBB-Institute for Biotechnology and Bioengineering, Centre for Biological Engineering, Minho University, Campus de Gualtar 4710-057, Braga, Portugal;

关键词: polymer;    delivery;    targeting;    self-assembly;    drugs;   

DOI  :  10.3390/ma3021420

来源: mdpi

【 摘 要 】

Hydrogel nanoparticles—also referred to as polymeric nanogels or macromolecular micelles—are emerging as promising drug carriers for therapeutic applications. These nanostructures hold versatility and properties suitable for the delivery of bioactive molecules, namely of biopharmaceuticals. This article reviews the latest developments in the use of self-assembled polymeric nanogels for drug delivery applications, including small molecular weight drugs, proteins, peptides, oligosaccharides, vaccines and nucleic acids. The materials and techniques used in the development of self-assembling nanogels are also described.

【 授权许可】

CC BY   
© 2010 by the authors; licensee MDPI, Basel, Switzerland.