Identification of Major Phenolic Compounds from Nephelium lappaceum L. and Their Antioxidant Activities

Molecules

Nont Thitilertdecha¹  Aphiwat Teerawutgulrag¹  Jeremy D. Kilburn¹ 

[1] ¹Division of Biotechnology, Graduate School, Chiang Mai University, Chiang Mai, 50200, Thailand ²Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand ³School of Chemistry, University of Southampton, Southampton, SO17 1BJ, UK

关键词: Nephelium lappaceum;    antioxidant;    geraniin;    corilagin;    ellagic acid;    phenolic compounds;   

DOI  :  10.3390/molecules15031453

来源: mdpi

【 摘 要 】

Nephelium lappaceum is a tropical fruit whose peel possesses antioxidant properties. Experiments on the isolation and identification of the active constituents were conducted, and on their antioxidant activity using a lipid peroxidation inhibition assay. The methanolic extract of N. lappaceum peels exhibited strong antioxidant properties. Sephadex LH-20 chromatography was utilized in the isolation of each constituent and the antioxidant properties of each was studied. The isolated compounds were identified as ellagic acid (EA) (1), corilagin (2) and geraniin (3). These compounds accounted for 69.3% of methanolic extract, with geraniin (56.8%) as the major component, and exhibited much greater antioxidant activities than BHT in both lipid peroxidation (77-186 fold) and DPPH^• (42-87 fold) assays. The results suggest that the isolated ellagitannins, as the principal components of rambutan peels, could be further utilized as both a medicine and in the food industry.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.