Optical Fiber LSPR Biosensor Prepared by Gold Nanoparticle Assembly on Polyelectrolyte Multilayer

Sensors

Yunliang Shao¹  Shuping Xu¹  Xianliang Zheng¹  Ye Wang¹ 

[1] State Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun 130012, China; E-Mails:

关键词: localized surface plasmon resonance (LSPR);    metal nanoparticle;    optical fiber sensor;    self-assembly;    immuno detection;   

DOI  :  10.3390/s100403585

来源: mdpi

【 摘 要 】

This article provides a novel method of constructing an optical fiber localized surface plasmon resonance (LSPR) biosensor. A gold nanoparticle (NP) assembled film as the sensing layer was built on the polyelectrolyte (PE) multilayer modified sidewall of an unclad optical fiber. By using a trilayer PE structure, we obtained a monodisperse gold NP assembled film. The preparation procedure for this LSPR sensor is simple and time saving. The optical fiber LSPR sensor has higher sensitivity and outstanding reproducibility. The higher anti-interference ability for response to an antibody makes it a promising method in application as a portable immuno-sensor.

【 授权许可】

CC BY   
© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.