Bioavailability of the Polyphenols: Status and Controversies

International Journal of Molecular Sciences

Massimo D𠆚rchivio¹  Carmelina Filesi²  Rosaria Varì²  Beatrice Scazzocchio² 

[1] Department of Veterinary Public Health and Food Safety, Italian National Institute of Health, Viale Regina Elena 299, 00161 Rome, Italy;

关键词: dietary polyphenols;    bioavailability;    metabolites;   

DOI  :  10.3390/ijms11041321

来源: mdpi

【 摘 要 】

The current interest in polyphenols has been driven primarily by epidemiological studies. However, to establish conclusive evidence for the effectiveness of dietary polyphenols in disease prevention, it is useful to better define the bioavailability of the polyphenols, so that their biological activity can be evaluated. The bioavailability appears to differ greatly among the various phenolic compounds, and the most abundant ones in our diet are not necessarily those that have the best bioavailability profile. In the present review, we focus on the factors influencing the bioavailability of the polyphenols. Moreover, a critical overview on the difficulties and the controversies of the studies on the bioavailability is discussed.

【 授权许可】

CC BY   
© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.