Chemical Composition and Biological Properties of Rhododendron anthopogon Essential Oil

Molecules

Gabbriella Innocenti¹  Stefano Dall’Acqua¹  Giuditta Scialino¹  Elena Banfi¹  Silvio Sosa¹  Khilendra Gurung¹  Mariagnese Barbera¹ 

[1] ¹Department of Pharmaceutical Sciences, University of Padova, Via F. Marzolo, 5, 35131 Padova, Italy

关键词: Rhododendron anthopogon;    GC-MS;    essential oil;    antimicrobial activity;    topical anti-inflammatory activity;    antiproliferative activity;   

DOI  :  10.3390/molecules15042326

来源: mdpi

【 摘 要 】

The essential oil of Rhododendron anthopogon was investigated by GC-MS, and seventeen compounds (representing approximately 98% of the oil) were identified. The major components of the aerial parts of the oil were the monoterpenes α-pinene, β-pinene, limonene and the sesquiterpene δ-cadinene. Biological studies revealed a weak topical anti-inflammatory activity; a significant killing effect against some Gram-positive reference strains: Staphylococcus aureus, Enterococcusfecalis, Bacillus subtilis was measured; Mycobacterium tuberculosis reference strain and a clinical isolate of Candida, C. pseudotropicalis were killed by as low as 0.04% (v/v) essential oil. Moreover, the oil was able to reduce cancer cell growth independently of the cell line and the treatment protocols used.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.