Cancers | |
Management of Melanoma Families | |
Wilma Bergman1  | |
关键词: : familial melanoma; hereditary melanoma; FAMMM syndrome; pancreatic carcinoma; management; surveillance; screening; DNA testing; CDKN2A; | |
DOI : 10.3390/cancers2020549 | |
来源: mdpi | |
【 摘 要 】
In this review we have aimed to focus on the clinical management of familial melanoma patients and their relatives. Along this line three major topics will be discussed: (1) management/screening of familial melanoma families: what is advised and what is the evidence thereof; (2) variability of families worldwide with regard to clinical phenotype, including cancer spectrum and likelihood of finding germline mutations and (3) background information for clinicians on the molecular biology of familial melanoma and recent developments in this field.
【 授权许可】
CC BY
© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190053983ZK.pdf | 228KB | download |