Molecules | |
Convenient and Efficient Microwave-Assisted Synthesis of a Methyl Derivative of the Fused Indoloquinoline Alkaloid Cryptosanguinolentine | |
Robert M. Gengan1  Pitchai Pandian1  Chandraprakash Kumarsamy1  | |
[1] 1Department of Chemistry, Steve Biko Campus, Durban University of Technology, Durban-4001, South Africa 2Department of Chemistry, School of Chemical Sciences, Bharathiar University, Coimbatore-641046, Tamil Nadu, India | |
关键词: cryptosanguinolentine; microwave; phase transfer catalysis; | |
DOI : 10.3390/molecules15053171 | |
来源: mdpi | |
【 摘 要 】
An efficient synthesis of a methyl derivative of the indoloquinoline alkaloid cryptosanguinolentine based on microwave-assisted reactions is described. The microwave-assisted synthesis of an intermediate 4-hydroxy-2-methylquinoline yielded 86% of the desired product and other intermediates prepared yielded high % of products in shorter reaction times, under optimum conditions, as compared to traditional methods.
【 授权许可】
CC BY
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
【 预 览 】
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RO202003190053701ZK.pdf | 313KB | download |