Micronutrients, N-Acetyl Cysteine, Probiotics and Prebiotics, a Review of Effectiveness in Reducing HIV Progression

Nutrients

Ruben Hummelen¹  Jaimie Hemsworth² 

[1] Department of Public Health, Erasmus MC University Medical Center Rotterdam P.O. Box 2040, 3000 CA Rotterdam, The Netherlands;Division of Food and Nutritional Sciences at Brescia University College, The University of Western Ontario, 1285 Western Road, N6G 1H2, London, Ontario, Canada;

关键词: HIV;    AIDS;    micronutrients;    zinc;    selenium;    N-acetyl cysteine;    probiotics;    prebiotics;   

DOI  :  10.3390/nu2060626

来源: mdpi

【 摘 要 】

Low serum concentrations of micronutrients, intestinal abnormalities, and an inflammatory state have been associated with HIV progression. These may be ameliorated by micronutrients, N-acetyl cysteine, probiotics, and prebiotics. This review aims to integrate the evidence from clinical trials of these interventions on the progression of HIV. Vitamin B, C, E, and folic acid have been shown to delay the progression of HIV. Supplementation with selenium, N-acetyl cysteine, probiotics, and prebiotics has considerable potential, but the evidence needs to be further substantiated. Vitamin A, iron, and zinc have been associated with adverse effects and caution is warranted for their use.

【 授权许可】

CC BY   
© 2010 by the authors; licensee MDPI, Basel, Switzerland