Eco-Contribution for the Production of N-Arylnitrones: Solvent-Free and Assisted by Microwaves

International Journal of Molecular Sciences

Leonor Reyes¹  Sandra Corona¹  Gabriel Arroyo¹  Francisco Delgado² 

[1] Departamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán-UNAM, Estado de México, 54754, Mexico; E-Mails:;Departamento de Química Orgánica, Escuela Nacional de Ciencia Biológicas-IPN, México D.F., 11340, Mexico; E-Mail:

关键词: green chemistry;    arylnitrones;    microwave;    solvent-less;    catalyst-less;   

DOI  :  10.3390/ijms11062576

来源: mdpi

【 摘 要 】

A simple green approach for the production of benzylideneaniline oxides is offered. This contribution was performed via the condensation of phenylhydroxylamine with several aryl aldehydes, in the absence of both catalyst and solvent, and using microwave irradiation as the activating reaction mode. In addition, good yields of the products were achieved in a short time. It is also worth noting that the work-up procedure is simple and the products do not require further purification. Finally, an interesting comparison without the use of microwave irradiation is also discussed.

【 授权许可】

CC BY   
© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.