Materials for Pharmaceutical Dosage Forms: Molecular Pharmaceutics and Controlled Release Drug Delivery Aspects

International Journal of Molecular Sciences

Heidi M. Mansour¹  MinJi Sohn²  Abeer Al-Ghananeem² 

[1] Division of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536, USA;

关键词: polymers;    copolymers;    biomaterials;    biodegradable;    microparticle;    nanoparticle;    pharmaceutical dosage forms;    particle engineering design;    manufacture;   

DOI  :  10.3390/ijms11093298

来源: mdpi

【 摘 要 】

Controlled release delivery is available for many routes of administration and offers many advantages (as microparticles and nanoparticles) over immediate release delivery. These advantages include reduced dosing frequency, better therapeutic control, fewer side effects, and, consequently, these dosage forms are well accepted by patients. Advances in polymer material science, particle engineering design, manufacture, and nanotechnology have led the way to the introduction of several marketed controlled release products and several more are in pre-clinical and clinical development.

【 授权许可】

CC BY   
© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.