International Journal of Molecular Sciences | |
Fabrication of Chitosan/Silk Fibroin Composite Nanofibers for Wound-dressing Applications | |
Zeng-xiao Cai1  Xiu-mei Mo1  Kui-hua Zhang1  Lin-peng Fan1  An-lin Yin1  Chuang-long He1  | |
[1] Key Laboratory of Textile Science & Technology, Ministry of Education, Donghua University, Shanghai, 201620, China; E-Mail: | |
关键词: electrospinning; chitosan; composite nanofibers; antibacterial activity; wound dressing; | |
DOI : 10.3390/ijms11093529 | |
来源: mdpi | |
【 摘 要 】
Chitosan, a naturally occurring polysaccharide with abundant resources, has been extensively exploited for various biomedical applications, typically as wound dressings owing to its unique biocompatibility, good biodegradability and excellent antibacterial properties. In this work, composite nanofibrous membranes of chitosan (CS) and silk fibroin (SF) were successfully fabricated by electrospinning. The morphology of electrospun blend nanofibers was observed by scanning electron microscopy (SEM) and the fiber diameters decreased with the increasing percentage of chitosan. Further, the mechanical test illustrated that the addition of silk fibroin enhanced the mechanical properties of CS/SF nanofibers. The antibacterial activities against
【 授权许可】
CC BY
© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190052194ZK.pdf | 1134KB | download |