Domoic Acid - A New Toxin in the Croatian Adriatic Shellfish Toxin Profile

Molecules

Ivana Ujević¹  Živana Ninčević-Gladan¹  Romana Roje¹  Sanda Skejić¹  Jasna Arapov¹ 

[1] ¹Institute of Oceanography and Fisheries, Šetalište I. Meštrovića 63, 21000 Split, Croatia P.O. Box 500, Croatia ²The Erasmus Mundus Master of Science in Marine Biodiversity and Conservation, Doverska 9, 21000 Split, Croatia

关键词: Amnesic shellfish poisoning (ASP);    retention of domoic acid;    mussels;    Pseudo-nitzschia;    Adriatic Sea;   

DOI  :  10.3390/molecules15106835

来源: mdpi

【 摘 要 】

This is the first study that presents concentrations of domoic acid detected in the whole shellfish tissue from breeding and harvesting areas along the Croatian coast of the Adriatic Sea during the period 2006 to 2008. Shellfish sample analyses after SAX cleaning procedures, using a UV-DAD-HPLC system, showed the presence of domoic acid in four species. The most prevalent of those species were the blue mussel (Mytilus galloprovincialis), followed by European flat oyster (Ostrea edulis), Mediterranean scallop (Pecten jacobaeus) and proteus scallop (Flexopecten proteus). Domoic acid, a potentially lethal phycotoxin that causes amnesic shellfish poisoning (ASP), was detected for the first time in January 2006 with the highest value of 6.5486 μg g^-1 in whole shellfish tissue. Pseudo-nitzschia spp. bloom events preceded these high domoic acid concentrations. According to this study, retention of domoic acid in the blue mussel M. galloprovincialis is more than 42 days. This investigation indicates the first presence of domoic acid in Croatian shellfish, but in concentrations under the regulatory limit (20 μg g^-1), therefore shellfish consumption was not found to endanger human health.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.