Anti-Fatigue Activity of Extracts of Stem Bark from Acanthopanax senticosus

Molecules

Xue-Ling Zhang¹  Feng Ren¹  Wei Huang¹  Ren-Tao Ding¹  Qiu-Sheng Zhou¹ 

[1] ¹Physical Education College, Zhengzhou University, Zhengzhou 450044, China ²Henan Ball Games Management Center, Zhengzhou 450044, China ³Henan Research Institute of Sport Science, Zhengzhou, 450044, China

关键词: anti-fatigue;    Acanthopanax senticosus;    forced swimming test;    mice;   

DOI  :  10.3390/molecules16010028

来源: mdpi

【 摘 要 】

In the present study, we investigated the anti-fatigue activity in male Kunming mice of extracts of stem bark from Acanthopanax senticosus (ASSE) using a forced swimming test. Mice were divided into four groups (three ASSE administered groups and the control group). The control group were gavaged with distilled water and ASSE administered groups were gavaged with ASSE (100, 200 and 400 mg/kg). After four weeks, a forced swimming test was performed and the biochemical parameters related to fatigue were examined. The results suggested that ASSE could extend the swimming time to exhaustion of the mice, as well as increase the tissue glycogen contents, while decreasing the blood lactate and serum urea nitrogen contents. This indicated that ASSE had anti-fatigue activity and could elevate the exercise tolerance.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.