Lipophilic Toxin Profile in Mytilus galloprovincialis during Episodes of Diarrhetic Shellfish Poisoning (DSP) in the N.E. Adriatic Sea in 2006

Molecules

Zivana Nincevic Gladan¹  Ivana Ujevic¹  Anna Milandri¹  Ivona Marasovic¹  Alfiero Ceredi¹  Silvia Pigozzi¹  Jasna Arapov¹ 

[1] ¹Institute of Oceanography and Fisheries, Šet. I. Meštrovića 63, 21000 Split, Croatia ²Fondazione Centro Ricerche Marine National Reference Laboratory on Marine Biotoxins, 47042 Cesenatico, Italy

关键词: diarrhetic shellfish poisoning;    okadaic acid;    Dinophysis fortii;    Adriatic sea;   

DOI  :  10.3390/molecules16010888

来源: mdpi

【 摘 要 】

Dinophysis spp. blooms and related shellfish toxicity events of diarrhetic shellfish poisoning (DSP) have been the most reported toxicity event through the Croatian National monitoring program. With the aim to characterize the DSP toxin profile in shellfish farmed in Croatia, for the first time a complete analysis of the toxin profile of Croatian mussels has been carried out using the LC-MS/MS technique. The obtained results showed okadaic acid (OA) as the main toxin contaminating Croatian mussels at that time. The maximum concentration of OA in shellfish tissue was recorded 12 days after the Dinophysis fortii bloom, thus suggesting that rapid growth of the toxin level in the shellfish occurred in the first week after the bloom while it was slower in the second week. Furthermore, the presence of only OA at concentrations which could endanger human health suggests D. fortii as the main organism responsible for the toxic event that occurred in Lim Bay. The presence of gymnodimine and spirolides in Croatian mussel has been detected for the first time, while the presence of yessotoxin and pectenotoxin-2 is confirmed.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.