Metabolic Resistance in Bed Bugs

Insects

Praveen Mamidala¹  Susan C. Jones² 

[1] Department of Entomology, The Ohio State University, Ohio Agricultural and Research Development Center, Wooster, OH 44691, USA; E-Mail:;Department of Entomology, The Ohio State University, Columbus, OH 43210, USA; E-Mail:

关键词: Cimex lectularius;    insecticides;    metabolic resistance;    cytochrome P450;    glutathione S-transferase;   

DOI  :  10.3390/insects2010036

来源: mdpi

【 摘 要 】

Blood-feeding insects have evolved resistance to various insecticides (organochlorines, pyrethroids, carbamates, etc.) through gene mutations and increased metabolism. Bed bugs (Cimex lectularius) are hematophagous ectoparasites that are poised to become one of the major pests in households throughout the United States. Currently, C. lectularius has attained a high global impact status due to its sudden and rampant resurgence. Resistance to pesticides is one factor implicated in this phenomenon. Although much emphasis has been placed on target sensitivity, little to no knowledge is available on the role of key metabolic players (e.g., cytochrome P450s and glutathione S-transferases) towards pesticide resistance in C. lectularius. In this review, we discuss different modes of resistance (target sensitivity, penetration resistance, behavioral resistance, and metabolic resistance) with more emphasis on metabolic resistance.

【 授权许可】

CC BY   
© 2011 by the authors; licensee MDPI, Basel, Switzerland.