Coccolithophores: Functional Biodiversity, Enzymes and Bioprospecting

Marine Drugs

Emma L. Reid¹  Charlotte A. Worthy¹  Ian Probert²  Sohail T. Ali¹  John Love³  Johnathan Napier⁴  Jenny A. Littlechild³  Paul J. Somerfield¹ 

[1] Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth, PL1 3DH, UK; E-Mails:;CNRS-UPMC Station Biologique de Roscoff, Place Georges Teissier, 29682 Roscoff Cedex, France; E-Mail:;College of Life and Environmental Science, Biosciences, University of Exeter, Exeter, EX4 4QD, UK; E-Mails:;Department of Biological Chemistry, Rothamsted Research, Harpenden, Herts AL5 2JQ, UK; E-Mails:

关键词: functional biodiversity;    bioprospecting;    biocatalysis;    coccolithophore;   

DOI  :  10.3390/md9040586

来源: mdpi

【 摘 要 】

Emiliania huxleyi is a single celled, marine phytoplankton with global distribution. As a key species for global biogeochemical cycling, a variety of strains have been amassed in various culture collections. Using a library consisting of 52 strains of E. huxleyi and an ‘in house’ enzyme screening program, we have assessed the functional biodiversity within this species of fundamental importance to global biogeochemical cycling, whilst at the same time determining their potential for exploitation in biocatalytic applications. Here, we describe the screening of E. huxleyi strains, as well as a coccolithovirus infected strain, for commercially relevant biocatalytic enzymes such as acid/alkali phosphodiesterase, acid/alkali phosphomonoesterase, EC1.1.1-type dehydrogenase, EC1.3.1-type dehydrogenase and carboxylesterase.

【 授权许可】

CC BY   
© 2011 by the authors; licensee MDPI, Basel, Switzerland.