Synthesis and Antifungal Activities of Some Novel Pyrimidine Derivatives

Molecules

Li Sun¹  Jie Wu¹  Lingzi Zhang¹  Min Luo¹ 

[1] Marine College, Shandong University, Weihai Wenhua West Road, No.180, Weihai 264209, China

关键词: pyrimidine derivatives;    synthesis;    antifungal activity;    SAR;   

DOI  :  10.3390/molecules16075618

来源: mdpi

【 摘 要 】

Three series of new pyrimidine derivatives were synthesized and their antifungal activities were evaluated in vitro against fourteen phytopathogenic fungi. The results indicated that most of the synthesized compounds possessed fungicidal activities and some of them are more potent than the control fungicides. Preliminary SAR was also discussed.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.