Trichothecenes: From Simple to Complex Mycotoxins

Toxins

Susan P. McCormick¹  April M. Stanley²  Nicholas A. Stover² 

[1] Bacterial Foodborne Pathogens and Mycology, National Center for Agricultural Utilization Research, U.S. Department of Agriculture-Agriculture Research Service, Peoria, IL 61604, USA;Biology Department, Bradley University, Peoria, IL 61625, USA;

关键词: trichothecenes;    mycotoxins;    Type A;    Type B;    macrocyclic;    d-type;    t-type;    toxin biosynthesis;   

DOI  :  10.3390/toxins3070802

来源: mdpi

【 摘 要 】

As the world’s population grows, access to a safe food supply will continue to be a global priority. In recent years, the world has experienced an increase in mycotoxin contamination of grains due to climatic and agronomic changes that encourage fungal growth during cultivation. A number of the molds that are plant pathogens produce trichothecene mycotoxins, which are known to cause serious human and animal toxicoses. This review covers the types of trichothecenes, their complexity, and proposed biosynthetic pathways of trichothecenes.

【 授权许可】

CC BY   
© 2011 by the authors; licensee MDPI, Basel, Switzerland.