Physicochemical Properties, in Vitro Antioxidant Activities and Inhibitory Potential against α-Glucosidase of Polysaccharides from Ampelopsis grossedentata Leaves and Stems

Molecules

Yuefei Wang¹  Xiaoying Bian¹  Jinhyouch Park¹  Le Ying¹  Lisheng Qian¹ 

[1] Department of Tea Science, Zhejiang University, Hangzhou 310058, China

关键词: polysaccharides;    Ampelopsis grossedentata;    physicochemical properties;    antioxidant activities;    α-glucosidase inhibition;   

DOI  :  10.3390/molecules16097762

来源: mdpi

【 摘 要 】

In the present study, polysaccharides named ALPS and ASPS were isolated from Ampelopsis grossedentata leaves and stems, respectively. Physicochemical properties, in vitro antioxidant activities and the inhibitory effects on α-glucosidase of ALPS and ASPS were investigated. It was found that both ALPS and ASPS were acid protein-bound heteropolysaccharides, although with considerably different chemical composition and molecular weight distribution. Meanwhile, in comparison with ALPS, ASPS exhibited stronger antioxidant activity and inhibitory potential against α-glucosidase according to the in vitro evaluation. Moreover, our results suggested that protein and uronic acid might, at least partly, contribute positively to the biological behavior of ALPS and ASPS.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.