Chemical and Metabolic Aspects of Antimetabolite Toxins Produced by Pseudomonas syringae Pathovars

Toxins

Eva Arrebola²  Francisco M. Cazorla¹  Alejandro Perez-Garc໚¹ 

[1] Instituto de Hortofruticultura Subtropical y Mediterránea “La Mayora” (IHSM-UMA-CSIC), Departamento de Microbiología, Facultad de Ciencias, Universidad de Málaga, Unidad Asociada al CSIC, Campus de Teatinos, Málaga 29071, Spain;;Instituto de Hortofruticultura Subtropical y Mediterránea “La Mayora” (IHSM-UMA-CSIC), Estación Experimental La Mayora, Algarrobo-Costa, Málaga 29750, Spain

关键词: tabtoxin;    phaseolotoxin;    mangotoxin;    virulence;    arginine;    ornithine;    glutamine;   

DOI  :  10.3390/toxins3091089

来源: mdpi

【 摘 要 】

Pseudomonas syringae is a phytopathogenic bacterium present in a wide variety of host plants where it causes diseases with economic impact. The symptoms produced by Pseudomonas syringae include chlorosis and necrosis of plant tissues, which are caused, in part, by antimetabolite toxins. This category of toxins, which includes tabtoxin, phaseolotoxin and mangotoxin, is produced by different pathovars of Pseudomonas syringae. These toxins are small peptidic molecules that target enzymes of amino acids’ biosynthetic pathways, inhibiting their activity and interfering in the general nitrogen metabolism. A general overview of the toxins’ chemistry, biosynthesis, activity, virulence and potential applications will be reviewed in this work.

【 授权许可】

CC BY   
© 2011 by the authors; licensee MDPI, Basel, Switzerland.