Marine Drugs | |
Studies on Synthesis and Structure-Activity Relationship (SAR) of Derivatives of a New Natural Product from Marine Fungi as Inhibitors of Influenza Virus Neuraminidase | |
Jing Li1  Dingmei Zhang3  Xun Zhu3  Zhenjian He3  Shu Liu2  Mengfeng Li3  Jiyan Pang1  | |
[1] School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China; E-Mail:;Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, 74 Zhongshan Road II, Guangzhou 510080, China; E-Mail:;Guangdong Province Key Laboratory of Functional Molecules in Oceanic Microorganism, Bureau of Education, Sun Yat-sen University, Guangzhou 510080, China; E-Mails: | |
关键词: aromatic ether; marine fungus; neuraminidase inhibitor; | |
DOI : 10.3390/md9101887 | |
来源: mdpi | |
【 摘 要 】
Based on the natural isoprenyl phenyl ether from a mangrove-derived fungus, 32 analogues were synthesized and evaluated for inhibitory activity against influenza H1N1 neuraminidase. Compound
【 授权许可】
CC BY
© 2011 by the authors; licensee MDPI, Basel, Switzerland
【 预 览 】
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