MAOS and Medicinal Chemistry: Some Important Examples from the Last Years

Molecules

Nailton M. Nascimento-Júnior¹  Arthur E. Kümmerle¹  Eliezer J. Barreiro¹ 

[1] ¹Laboratório de Avaliação e Síntese de substâncias Bioativas (LASSBio), Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, PO Box 68023, Rio de Janeiro 21941-902, RJ, Brazil

关键词: microwave irradiation;    medicinal chemistry;    bioactive compounds;    drug discovery;   

DOI  :  10.3390/molecules16119274

来源: mdpi

【 摘 要 】

This review aims to highlight microwave-assisted organic synthesis as applied to medicinal chemistry in the last years, showing some reactions performed under microwave irradiation for the synthesis of distinct structurally molecules of biological interest, divided into the following groups: antineoplastics, anti-inflammatory, antimicrobial agents, antivirals, agents for the treatment of neglected diseases and central nervous system-acting prototypes.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.