Pharmaceutics | |
Exploring the Correlation Between Lipid Packaging in Lipoplexes and Their Transfection Efficacy | |
Behfar Moghaddam1  Sarah E. McNeil1  Qinguo Zheng1  Afzal R. Mohammed1  | |
[1] id="af1-pharmaceutics-03-00848">School of Life and Health Sciences, Aston University, Birmingham, B4 7ET, | |
关键词: Langmuir studies; lipid packaging; cationic liposomes; gene delivery; transfection; electrolytes; | |
DOI : 10.3390/pharmaceutics3040848 | |
来源: mdpi | |
【 摘 要 】
Whilst there is a large body of evidence looking at the design of cationic liposomes as transfection agents, correlates of formulation to function remain elusive. In this research, we investigate if lipid packaging can give further insights into transfection efficacy. DNA lipoplexes composed of 1,2-dioleoyl-
【 授权许可】
CC BY
© 2011 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190047134ZK.pdf | 1107KB | download |