Overview of Stabilizing Ligands for Biocompatible Quantum Dot Nanocrystals

Sensors

Yanjie Zhang¹ 

[1] Department of Chemical and Biological Engineering, Iowa State University, Ames, IA50011, USA; E-Mail

关键词: quantum dots;    ligand;    biocompatible;   

DOI  :  10.3390/s111211036

来源: mdpi

【 摘 要 】

Luminescent colloidal quantum dots (QDs) possess numerous advantages as fluorophores in biological applications. However, a principal challenge is how to retain the desirable optical properties of quantum dots in aqueous media while maintaining biocompatibility. Because QD photophysical properties are directly related to surface states, it is critical to control the surface chemistry that renders QDs biocompatible while maintaining electronic passivation. For more than a decade, investigators have used diverse strategies for altering the QD surface. This review summarizes the most successful approaches for preparing biocompatible QDs using various chemical ligands.

【 授权许可】

CC BY   
© 2011 by the authors; licensee MDPI, Basel, Switzerland.