Biotransformation of (1S)-2-Carene and (1S)-3-Carene by Picea abies Suspension Culture

Molecules

Marcela Dvorakova¹  Irena Valterova¹  David Saman¹ 

[1] ¹Laboratory of Plant Biotechnologies, Joint Laboratory of Institute of Experimental Botany, Academy of Sciences of the Czech Republic, v.v.i., and Research Institute of Crop Production, v.v.i., Rozvojova 263, 165 02 Prague 6, Czech Republic

关键词: biotransformation;    carene;    oxidation;    Picea abies;   

DOI  :  10.3390/molecules161210541

来源: mdpi

【 摘 要 】

Biotransformation of (1S)-2-carene and (1S)-3-carene by Picea abies suspension culture led to the formation of oxygenated products. (1S)-2-Carene was transformed slowly and the final product was identified as (1S)-2-caren-4-one. On the other hand, the transformation of (1S)-3-carene was rapid and finally led to the formation of (1S)-3-caren-5-one and (1S)-2-caren-4-one as equally abundant major products. The time-course of the reaction indicates that some products abundant at the beginning of the reaction (e.g. (1S,3S,4R)-3,4-epoxycarane and (1R)-p-mentha-1(7),2-dien-8-ol) were consumed by a subsequent transformations. Thus, a precise selection of the biotransformation time may be used for a production of specific compounds.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.