Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis

International Journal of Molecular Sciences

Li-Yin Chen¹  Ih-Sheng Chen² 

[1] Department of Pharmacy, Chia-Nan University of Pharmacy and Science, Tainan 71710, Taiwan;School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan; E-Mail:

关键词: Wikstroemia taiwanensis;    Thymelaeaceae;    stem;    biflavonoid;    antitubercular activity;   

DOI  :  10.3390/ijms13011029

来源: mdpi

【 摘 要 】

Three new biflavonoids, wikstaiwanones A–C (1–3), along with four known compounds (4–7) were isolated from the stems of Wikstroemia taiwanensis (Thymelaeaceae). Their structures were elucidated by spectroscopic analysis. Compounds 4 and 5 showed antitubercular activity against Mycobacterium tuberculosis with MIC values of 15 μg/mL, respectively.

【 授权许可】

CC BY   
© 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.