Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors

International Journal of Molecular Sciences

John A. Sandoval²  Linda H. Malkas¹ 

[1] City of Hope Cancer Center, Duarte, CA 91010, USA; E-Mails:;Department of Surgery, St. Jude Children’s Research Hospital, 262 Danny Thomas Place, MS332, Room D3040G, Memphis, TN 38105, USA

关键词: pediatric solid tumors;    mediastinal mass;    abdominal mass;    serum biomarkers;   

DOI  :  10.3390/ijms13011126

来源: mdpi

【 摘 要 】

Childhood cancer is the leading cause of death by disease among U.S. children between infancy and age 15. Despite successes in treating solid tumors such as Wilms tumor, disappointments in the outcomes of high-risk solid tumors like neuroblastoma have precipitated efforts towards the early and accurate detection of these malignancies. This review summarizes available solid tumor serum biomarkers with a special focus on mediastinal and abdominal cancers in children.

【 授权许可】

CC BY   
© 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.