Chiroptical Switches: Applications in Sensing and Catalysis

Molecules

Zhaohua Dai¹  Jennifer Lee¹ 

[1] ¹Department of Chemistry and Physical Sciences, Pace University, 1 Pace Plaza, New York, NY 10038, USA ²Department of Chemistry, New York University, 100 Washington Square East, New York, NY 10003, USA

关键词: chiroptical switches;    molecular recognition;    sensor;    chiral analyte;    achiral analyte;    asymmetric catalysis;   

DOI  :  10.3390/molecules17021247

来源: mdpi

【 摘 要 】

Chiroptical switches have found application in the detection of a multitude of different analytes with a high level of sensitivity and in asymmetric catalysis to offer switchable stereoselectivity. A wide range of scaffolds have been employed that respond to metals, small molecules, anions and other analytes. Not only have chiroptical systems been used to detect the presence of analytes, but also other properties such as oxidation state and other physical phenomena that influence helicity and conformation of molecules and materials. Moreover, the tunable responses of many such chiroptical switches enable them to be used in the controlled production of either enantiomer or diastereomer at will in many important organic reactions from a single chiral catalyst through selective use of a low-cost inducer: Co-catalysts (guests), metal ions, counter ions or anions, redox agents or electrochemical potential, solvents, mechanical forces, temperature or electromagnetic radiation.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.