Synthetic Strategies to Terpene Quinones/Hydroquinones

Marine Drugs

关键词: terpene quinone;    terpene hydroquinone;    synthesis;    chemical modification;   

DOI  :  10.3390/md10020358

来源: mdpi

【 摘 要 】

The cytotoxic and antiproliferative properties of many natural sesquiterpene-quinones and -hydroquinones from sponges offer promising opportunities for the development of new drugs. A review dealing with different strategies for obtaining bioactive terpenyl quinones/hydroquinones is presented. The different synthetic approches for the preparation of the most relevant quinones/hydroquinones are described.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.