Cancers | |
Epithelial-Mesenchymal Transition Is a Critical Step in Tumorgenesis of Pancreatic Neuroendocrine Tumors | |
Volker Fendrich1  Katja Maschuw1  Jens Waldmann1  Malte Buchholz2  Johannes Rehm1  Thomas M. Gress2  Detlef K. Bartsch1  | |
[1] Department of Surgery, Philipps University Marburg, Baldingerstraße, Marburg D-35043, Germany;Department of Gastroenterology and Endocrinology, Philipps-University Marburg, Baldingerstraße, Marburg D-35043, Germany | |
关键词: EMT; E-cadherin; snail; slug; twist; Rip1Tag2; PEG; | |
DOI : 10.3390/cancers4010281 | |
来源: mdpi | |
【 摘 要 】
The transcription factors Snail, Slug and Twist repress E-cadherin and induce epithelial-mesenchymal transition (EMT), a process exploited by invasive cancer cells. In this study, we evaluated the role of EMT in the tumorgenesis of neuroendocrine tumors of the pancreas (PNETs)
【 授权许可】
CC BY
© 2012 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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RO202003190045429ZK.pdf | 3699KB | download |