Functionalized Nanostructures with Application in Regenerative Medicine

International Journal of Molecular Sciences

Macarena Perán³  Mar໚ A. Garc໚¹  Elena López-Ruiz³  Milán Bustamante⁵  Gema Jiménez⁴  Roberto Madeddu² 

[1] Research Unit, Hospital Universitario Virgen de las Nieves, Granada E-18014, Spain; E-Mail:;Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy; E-Mail:;Department of Health Sciences, University of Jaén, Jaén E-23071, Spain; E-Mails:;Biopathology and Regenerative Medicine Institute (IBIMER), Biomedical Research Centre, University of Granada, Granada E-18100, Spain; E-Mail:;Biosciences Institute, University College Cork, Cork, Ireland; E-Mail:

关键词: regenerative medicine;    nanomaterials;    scaffolds;    cell therapy;    stem cells;    bone;    cartilage;    cell encapsulation;    cell tracking;    gene and drug delivery;   

DOI  :  10.3390/ijms13033847

来源: mdpi

【 摘 要 】

In the last decade, both regenerative medicine and nanotechnology have been broadly developed leading important advances in biomedical research as well as in clinical practice. The manipulation on the molecular level and the use of several functionalized nanoscaled materials has application in various fields of regenerative medicine including tissue engineering, cell therapy, diagnosis and drug and gene delivery. The themes covered in this review include nanoparticle systems for tracking transplanted stem cells, self-assembling peptides, nanoparticles for gene delivery into stem cells and biomimetic scaffolds useful for 2D and 3D tissue cell cultures, transplantation and clinical application.

【 授权许可】

CC BY   
© 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.