Metabolites | |
Targeted Chiral Analysis of Bioactive Arachidonic Acid Metabolites Using Liquid-Chromatography-Mass Spectrometry | |
Clementina Mesaros1  | |
[1] Centers for Cancer Pharmacology and Excellence in Environmental Toxicology, Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA; | |
关键词: arachidonic acid; eicosanoids; chiral liquid chromatography; tandem mass spectrometry; selected reaction monitoring; atmospheric pressure chemical ionization; electron capture; cyclooxygenase; lipoxygenase; cytochrome P-450; | |
DOI : 10.3390/metabo2020337 | |
来源: mdpi | |
【 摘 要 】
A complex structurally diverse series of eicosanoids arises from the metabolism of arachidonic acid. The metabolic profile is further complicated by the enantioselectivity of eicosanoid formation and the variety of regioisomers that arise. In order to investigate the metabolism of arachidonic acid
【 授权许可】
CC BY
© 2012 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190044979ZK.pdf | 942KB | download |