In Vitro Phytotoxicity and Antioxidant Activity of Selected Flavonoids

International Journal of Molecular Sciences

Laura De Martino²  Teresa Mencherini²  Emilia Mancini²  Rita Patrizia Aquino²  Luiz Fernando Rolim De Almeida¹ 

[1] Departamento de Botânica, Instituto de Biociências de Botucatu, UNESP-Campu de Botucatu Distrito de Rubião Júnior, S/N, 18.618-000, Botucatu-SP, Brazil; E-Mail:;Dipartimento di Scienze Farmaceutiche e Biomediche, Università degli Studi di Salerno, Via Ponte don Melillo, 84084 Fisciano, Salerno, Italy; E-Mails:

关键词: flavonoids;    germination;    radical elongation;    antioxidant activity;    structure/activity;   

DOI  :  10.3390/ijms13055406

来源: mdpi

【 摘 要 】

The knowledge of flavonoids involved in plant-plant interactions and their mechanisms of action are poor and, moreover, the structural characteristics required for these biological activities are scarcely known. The objective of this work was to study the possible in vitro phytotoxic effects of 27 flavonoids on the germination and early radical growth of Raphanus sativus L. and Lepidium sativum L., with the aim to evaluate the possible structure/activity relationship. Moreover, the antioxidant activity of the same compounds was also evaluated. Generally, in response to various tested flavonoids, germination was only slightly affected, whereas significant differences were observed in the activity of the various tested flavonoids against radical elongation. DPPH test confirms the antioxidant activity of luteolin, quercetin, catechol, morin, and catechin. The biological activity recorded is discussed in relation to the structure of compounds and their capability to interact with cell structures and physiology. No correlation was found between phytotoxic and antioxidant activities.

【 授权许可】

CC BY   
© 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.