Preparation of SRN1-Type Coupling Adducts from Aliphatic gem-Dinitro Compounds in Ionic Liquids

Molecules

Akio Kamimura¹ 

[1] Department of Applied Molecular Bioscience, Graduate School of Medicine, Yamaguchi University, Ube 755-8611, Japan

关键词: S_RN1-type adducts;    ionic liquids;    nitro compounds;    kinetics;   

DOI  :  10.3390/molecules17054782

来源: mdpi

【 摘 要 】

S_RN1-type coupling adducts are readily prepared by the reaction between a-sulfonylesters or a-cyanosulfones and gem-dinitro compounds in ionic liquids. The reactions progress smoothly and recovered ionic liquids can be used for several iterations, as long as they are washed with water to remove alkali metallic salts. The reaction rate is slower than the corresponding S_RN1 reaction in DMSO, but no acceleration on irradiation or no inhibition in the presence of m-DNB are observed.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.