Molbank | |
7-{[2-(4-Hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid | |
Ghulam Fareed1  Mahboob A. Kalhoro1  Muhammad A. Versiani1  Nighat Afza1  | |
[1] 1Pharmaceutical Research Center, PCSIR Laboratories Complex Karachi, Shahrah-e-Dr.Salim-uz-Zaman Siddiqui Karachi-75280. Sindh, Pakistan 2Department of Chemistry, Federal Urdu University of Arts, Science and Technology, Ghulshan-e-Iqbal, Karachi-75300. Sindh, Pakistan | |
关键词: ceftriaxone; 4-hydroxybenzaldehyde; | |
DOI : 10.3390/M756 | |
来源: mdpi | |
【 摘 要 】
Novel 7-{[2-(4-hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1azabicyclo [4.2.0]oct-2-ene-2-carboxylic acid was prepared by condensation of ceftriaxone disodium (1) with 4-hydroxybenzaldehyde (2) in ethanol under reflux conditions for 3–4 h. The structure of synthesized compound was elucidated using LCMS, 1H-NMR, and CHN techniques.
【 授权许可】
CC BY
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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