7-{[2-(4-Hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

Molbank

Ghulam Fareed¹  Mahboob A. Kalhoro¹  Muhammad A. Versiani¹  Nighat Afza¹ 

[1] ¹Pharmaceutical Research Center, PCSIR Laboratories Complex Karachi, Shahrah-e-Dr.Salim-uz-Zaman Siddiqui Karachi-75280. Sindh, Pakistan ²Department of Chemistry, Federal Urdu University of Arts, Science and Technology, Ghulshan-e-Iqbal, Karachi-75300. Sindh, Pakistan

关键词: ceftriaxone;    4-hydroxybenzaldehyde;   

DOI  :  10.3390/M756

来源: mdpi

【 摘 要 】

Novel 7-{[2-(4-hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1azabicyclo [4.2.0]oct-2-ene-2-carboxylic acid was prepared by condensation of ceftriaxone disodium (1) with 4-hydroxybenzaldehyde (2) in ethanol under reflux conditions for 3–4 h. The structure of synthesized compound was elucidated using LCMS, ¹H-NMR, and CHN techniques.

【 授权许可】

CC BY   
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