Journal of Functional Biomaterials | |
Ceramic Identity Contributes to Mechanical Properties and Osteoblast Behavior on Macroporous Composite Scaffolds | |
Diana G. Morales-Hernandez2  Damian C. Genetos1  David M. Working2  Kaitlin C. Murphy2  | |
[1] Department of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA;Department of Biomedical Engineering, University of California, Davis, CA 95616, USA; | |
关键词: bioceramic; hydroxyapatite; bioactive glass; composite; scaffold; bone; | |
DOI : 10.3390/jfb3020382 | |
来源: mdpi | |
【 摘 要 】
Implants formed of metals, bioceramics, or polymers may provide an alternative to autografts for treating large bone defects. However, limitations to each material motivate the examination of composites to capitalize on the beneficial aspects of individual components and to address the need for conferring bioactive behavior to the polymer matrix. We hypothesized that the inclusion of different bioceramics in a ceramic-polymer composite would alter the physical properties of the implant and the cellular osteogenic response. To test this, composite scaffolds formed from poly(lactide-
【 授权许可】
CC BY
© 2012 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190043990ZK.pdf | 844KB | download |