Phytochemical and Biological Studies of Agave attenuata

International Journal of Molecular Sciences

Komal Rizwan¹  Muhammad Zubair¹  Nasir Rasool¹  Muhammad Riaz¹  Muhammad Zia-Ul-Haq² 

[1] Department of Chemistry, Government College University, Faisalabad 38000, Pakistan; E-Mails:;Research Institute of Pharmaceutical Sciences, Department of Pharmacognosy, University of Karachi, Karachi 75270, Pakistan; E-Mail:

关键词: Agave attenuata;    GC-MS;    peroxidation;    volatile fraction;    flavonoids;    phenolics;   

DOI  :  10.3390/ijms13056440

来源: mdpi

【 摘 要 】

The present study was conducted to examine various biological activities of a methanol extract of Agave attenuata leaves. GC-MS analysis of the n-hexane fraction from the extract revealed the presence of 31 compounds, with mono-2-ethylhexyl phthalate (11.37%), 1,2-benzenedicarboxylic acid (6.33%), n-docosane (6.30%) and eicosane (6.02%) as the major components. The leaves contained appreciable levels of total phenolic contents (10.541–39.35 GAE, mg/100 g) and total flavonoid contents (43.35–304.8 CE, mg/100 g). The extract and some of its fractions showed moderate antimicrobial effects. Leaves extract and fractions also exhibited a good antioxidant potential when measured by DPPH radical scavenging activity and inhibition of lipid peroxidation assays. The hemolytic effect of the plant was found to be in a range of 1.01%–2.64%. From the present study it is concluded that this plant could be used as a source of natural antioxidants and functional food nutraceutical applications.

【 授权许可】

CC BY   
© 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.