Recent Progress in Studies of Arterivirus- and Coronavirus-Host Interactions

Viruses

Yanxin Zhong¹  Yong Wah Tan¹ 

[1] School of Biological Sciences, Nanyang Technological Sciences, 60 Nanyang Drive, Singapore 637551, Singapore;

关键词: virus-host interactions;    coronavirus;    arterivirus;   

DOI  :  10.3390/v4060980

来源: mdpi

【 摘 要 】

Animal coronaviruses, such as infectious bronchitis virus (IBV), and arteriviruses, such as porcine reproductive and respiratory syndrome virus (PRRSV), are able to manifest highly contagious infections in their specific native hosts, thereby arising in critical economic damage to animal industries. This review discusses recent progress in studies of virus-host interactions during animal and human coronavirus and arterivirus infections, with emphasis on IBV-host cell interactions. These interactions may be directly involved in viral replication or lead to the alteration of certain signaling pathways, such as cell stress response and innate immunity, to facilitate viral replication and pathogenesis.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.