Multi-Faceted Post-Transcriptional Functions of HIV-1 Rev

Biology

关键词: Rev;    CRM1;    DDX3;    RNA export;    RNA translation;    RNA packaging;   

DOI  :  10.3390/biology1020165

来源: mdpi

【 摘 要 】

Post-transcriptional regulation of HIV-1 gene expression is largely governed by the activities of the viral Rev protein. In this minireview, the multiple post-transcriptional activities of Rev in the export of partially spliced and unspliced HIV-1 RNAs from the nucleus to the cytoplasm, in the translation of HIV-1 transcripts, and in the packaging of viral genomic RNAs are reviewed in brief.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.