Marine Drugs | |
Preparation and Characterization of |
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Na Gao1  Mingyi Wu1  Shao Liu2  Wu Lian1  Zi Li1  | |
[1] State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;School of Pharmaceutical Sciences, Central South University, Changsha 410078, China; | |
关键词: sea cucumber; fucosylated chondroitin sulfate; glycosaminoglycan; acylation; anticoagulant activity; | |
DOI : 10.3390/md10081647 | |
来源: mdpi | |
【 摘 要 】
Fucosylated chondroitin sulfate (FuCS), a kind of complex glycosaminoglycan from sea cucumber, has potent anticoagulant activity. In order to understand the relationship between structures and activity, the depolymerized FuCS (dFuCS) was chosen to prepare its derivates by selective substitution at OH groups. Its
【 授权许可】
CC BY
© 2012 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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