Cyclodextrin-Based [1]Rotaxanes on Gold Nanoparticles

International Journal of Molecular Sciences

Liangliang Zhu¹  Hong Yan¹ 

[1] Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371, Singapore; E-Mails:

关键词: azobenzene;    complexation;    cyclodextrin;    gold nanoparticle;    [1]rotaxane;   

DOI  :  10.3390/ijms130810132

来源: mdpi

【 摘 要 】

Transformation of mechanically interlocked molecules (e.g., rotaxanes and catenanes) into nanoscale materials or devices is an important step towards their real applications. In our current work, an azobenzene-modified β-cyclodextrin (β-CD) derivative that can form a self-inclusion complex in aqueous solution was prepared. The self-included β-CD derivative was then functionalized onto a gold nanoparticle (AuNP) surface via a ligand-exchange reaction in aqueous solution, leading to the formation of AuNP-[1]rotaxane hybrids. Corresponding non-self-included β-CD derivative functionalized AuNPs were also developed in a DMF/H₂O mixture solution for control experiments. These hybrids were fully characterized by UV-vis and circular dichroism spectroscopies, together with transmission electron microscopy (TEM). The competitive binding behavior of the hybrids with an adamantane dimer was investigated.

【 授权许可】

CC BY   
© 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.