Brain Sciences | |
Neurochemical Analysis of Primary Motor Cortex in Chronic Low Back Pain | |
Neena K. Sharma6  William M. Brooks2  Anda E. Popescu5  Linda VanDillen1  Steven Z. George3  Kenneth E. McCarson4  Byron J. Gajewski7  Patrick Gorman6  | |
[1] Program in Physical Therapy, Washington University Medical School, St. Louis, MO 63108, USA;Department of Neurology, University of Kansas Medical Center, Kansas City, KS 66160, USA;Department of Physical Therapy, University of Florida, Gainesville, FL 32611, USA;Department of Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA;Hoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS 66160, USA;Department of Physical Therapy & Rehabilitation Sciences, University of Kansas Medical Center, Kansas City, KS 66160, USA;Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS 66160, USA; | |
关键词:
chronic low back pain;
primary motor cortex;
magnetic resonance spectroscopy;
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DOI : 10.3390/brainsci2030319 | |
来源: mdpi | |
【 摘 要 】
The involvement of the primary motor cortex (M1) in chronic low back pain (LBP) is a relatively new concept. Decreased M1 excitability and an analgesic effect after M1 stimulation have been recently reported. However, the neurochemical changes underlying these functional M1 changes are unknown. The current study investigated whether neurochemicals specific to neurons and glial cells in both right and left M1 are altered.
【 授权许可】
CC BY
© 2012 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190042413ZK.pdf | 333KB | download |