Effects of Two Different Levels of Dietary Protein on Body Composition and Protein Nutritional Status of Growing Rats

Nutrients

Julio Tirapegui¹  Sandra Maria Lima Ribeiro²  Ivanir Santana de Oliveira Pires¹ 

[1] Department of Food Science and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, SP, CEP 05508-000, Brazil;School of Arts, Sciences and Humanities, University of São Paulo, São Paulo, SP, CEP 03828-000, Brazil;

关键词: dietary protein;    protein nutritional status;    growth;    body composition;   

DOI  :  10.3390/nu4091328

来源: mdpi

【 摘 要 】

This study aimed to investigate the effect of a high-protein diet on growth, body composition, and protein nutritional status of young rats. Newly-weaned Wistar rats, weighing 45–50 g, were distributed in two experimental groups, according to their diets, which contained 12% (G12) or 26% protein (G26), over a period of 3 weeks. The animals were euthanized at the end of this period and the following analyses were performed: chemical composition of the carcass, proteoglycan synthesis, IGF-I concentration (serum, muscle and cartilage), total tissue RNA, protein concentration (muscle and cartilage) and protein synthesis (muscle and cartilage). The high-protein diet was found to result in a higher fat-free mass and lower fat mass in the carcass, with no difference in growth or protein nutritional status.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.