Organophosphorus Chemistry for the Synthesis of Dendrimers

Molecules

Anne-Marie Caminade¹  Régis Laurent¹  Maria Zablocka¹ 

[1] ¹Laboratoire de Chimie de Coordination), 205 route de Narbonne, BP44099, F-31077 Toulouse Cedex 4, France ²Université de Toulouse, UPS, INPT, F-31077 Toulouse Cedex 4, France ³Centre of Molecular and Macromolecular Studies, The Polish Academy of Sciences, Sienkiewicza 112, 90363 Lodz, Poland

关键词: dendrimers;    phosphorus;    hydrazone;    phosphine;    phosphonate;   

DOI  :  10.3390/molecules171113605

来源: mdpi

【 摘 要 】

Dendrimers are multifunctional, hyperbranched and perfectly defined macromolecules, synthesized layer after layer in an iterative manner. Besides the nature of the terminal groups responsible for most of the properties, the nature of the internal structure, and more precisely of the branching points, is also of crucial importance. For more than 15 years, we have demonstrated that the presence of phosphorus atom(s) at each branching point of the dendrimeric structure is particularly important and highly valuable for three main reasons: (i) the versatility of phosphorus chemistry that allows diversified organochemistry for the synthesis of dendrimers; (ii) the use of ³¹P-NMR, which is a highly valuable tool for the characterization of dendrimers; (iii) some properties (in the fields of catalysis, materials, and especially biology), that are directly connected to the nature of the internal structure and of the branching points. This review will give an overview of the methods of synthesis of phosphorus-containing dendrimers, as well on the ways to graft phosphorus derivatives as terminal groups, with emphasis on the various roles played by the chemistry of phosphorus.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.