Clerodendranoic Acid, a New Phenolic Acid from Clerodendranthus spicatus

Molecules

Qingxia Zheng¹  Zhaocui Sun¹  Xiaopo Zhang¹  Jinquan Yuan¹  Haifeng Wu¹  Junshan Yang¹ 

[1] ¹Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China

关键词: Clerodendranthus spicatus;    Lamiaceae;    phenolic compounds;   

DOI  :  10.3390/molecules171113656

来源: mdpi

【 摘 要 】

Phenolic acid derivatives are typical constituents of Clerodendranthus spicatus which were considered to the active principles of this medicinal plant. These chemical constituents with their interesting frameworks and biological significance attracted our attention. As part of our ongoing chemical investigation of C. spicatus using various column chromatography techniques, a new phenolic compound, named clerodendranoic acid (1), was isolated from the aerial parts of C. spicatus together with five known ones, including rosmarinic acid (2), methyl rosmarinate (3), caffeic acid (4), methyl caffeate (5), ethyl caffeate (6). Their structures, including stereochemical configurations, were completely established by extensive spectroscopic methods, mainly inclvolving 1D, 2D NMR, as well as HRESIMS.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.