Materials | |
Cell-Sized Liposomes and Droplets: Real-World Modeling of Living Cells | |
Tsutomu Hamada1  | |
[1] School of Materials Science,Japan Advanced Institute of Science and Technology, 1-1, Asahidai, Nomi, Ishikawa 923-1292, Japan | |
关键词: liposome; droplet; cell-sized confinement; lipid membrane; DNA; compartmentalization; nanoparticle; | |
DOI : 10.3390/ma5112292 | |
来源: mdpi | |
【 摘 要 】
Recent developments in studies concerning cell-sized vesicles, such as liposomes with a lipid bilayer and water-in-oil droplets covered by a lipid monolayer, aim to realize the real-world modeling of living cells. Compartmentalization with a membrane boundary is essential for the organization of living systems. Due to the relatively large surface/volume ratio in microconfinement, the membrane interface influences phenomena related to biological functions. In this article, we mainly focus on the following subjects: (i) conformational transition of biopolymers in a confined space; (ii) molecular association on the membrane surface; and (iii) remote control of cell-sized membrane morphology.
【 授权许可】
CC BY
© 2012 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190040278ZK.pdf | 877KB | download |