期刊论文详细信息
Molecules
Synthesis and Antiradical/Antioxidant Activities of Caffeic Acid Phenethyl Ester and Its Related Propionic, Acetic, and Benzoic Acid Analoguesc
Luc M. LeBlanc1  Aurélie F. Paré1  Jacques Jean-François1  Martin J. G. Hébert1  Marc E. Surette1 
[1] Department of Chemistry and Biochemistry, Université de Moncton, Moncton, NB E1A 3E9, Canada
关键词: CAPE;    caffeic acid;    3-(3;    4-dihydroxyphenyl) propanoic acid esters;    2-(3;    4-dihydroxyphenyl) acetic acid esters;    3;    4-dihydroxybenzoic acid esters;    antioxidant;   
DOI  :  10.3390/molecules171214637
来源: mdpi
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【 摘 要 】

Caffeic acid phenethyl ester (CAPE) is a bioactive component isolated from propolis. A series of CAPE analogues was synthesized and their antiradical/antioxidant effects analyzed. The effect of the presence of the double bond and of the conjugated system on the antioxidant effect is evaluated with the analogues obtained from 3-(3,4-dihydroxyphenyl) propanoic acid. Those obtained from 2-(3,4-dihydroxyphenyl) acetic acid and 3,4-dihydroxybenzoic acid allow the evaluation of the effect of the presence of two carbons between the carbonyl and aromatic system.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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