Entropy Stress and Scaling of Vital Organs over Life Span Based on Allometric Laws

Entropy

Kalyan Annamalai¹ 

关键词: bio-thermodynamics;    organ;    life span;    entropy generation;    ageing;    biological system;   

DOI  :  10.3390/e14122550

来源: mdpi

【 摘 要 】

Past theories on total lifetime energy expenditures and entropy generation in biological systems (BS) dealt with whole systems, but the recent literature suggests that the total metabolic rate of a BS,the organs were ranked from highest to lowest entropy generation and the heart is found to be the most entropy-stressed organ. The entropy stress levels of the other organs are then normalized to the entropy stress level (NES_H) of the heart. The NES_H values for organs are as follows: Heart: 1.0, Kidney: 0.92, Brain: 0.46, Liver: 0.41, Rest of BS: 0.027. If normalized to rest of body (R), NES_R, heart: 37, Kidney: 34, Brain: 17, Liver: 15, Rest of BS: 1.0; so heart will fail first followed by kidney and other organs in order. Supporting data is provided.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.